Department of Biotechnology

The Department of Biotechnology came in existence under the School of Life Sciences at Central University of Rajasthan in July 2011. The Master’s program in Biotechnology was started as the flagship program of the department with immediate effect. In the following academic year, 2012-13,Ph.D. program was introduced and then in academic year 2013-14 an integrated M.Sc. programme was also initiated.

The department has well equipped laboratories for Ph.D., M.Sc. and integrated M.Sc. students. The department has a total of ten highly qualified and enthusiastic faculty members already on board. With continuous development and expansion of its scientific infrastructure and learned faculty, the department aims to become one of the shining beacons of the University and the nation in the near future.

News & Announcements

Welcome to Department of Biotechnology

Important Links

MSc Biotechnology Syllabus with CO and PO [To be effective from Academic Session 2022-2023]

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Pre-Ph.D course work Syllabus 2020-21

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M.Sc Biotechnology Syllabus 2020-21

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Integrated M.Sc. Programme V & VI Semester Syllabus

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E-Prospectus

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MSc Biotechnology

Eligibility:

Bachelor’s degree with Microbiology/Zoology/Botany/Life sciences / Biochemistry/ Genetics/ Biotechnology/ Medicine/ Pharmacy/ any other discipline of Biological sciences as one of the main subjects and Chemistry as one of the optional subjects at least for One year or Two semesters with minimum 50% of marks or equivalent grade in aggregate for general category and 45% or equivalent grade for SC/ST/OBC/PWD/EWS candidates

syllabus-22-23.pdf

Integrated M. Sc. Biotechnology (5 years Program)

Ten integrated M.Sc. programmes were started parallely. Out of these programmes, seven programme viz. Biotechnology, Microbiology, Biochemistry, Environmental Science, Physics, Chemistry and Mathematics share same course framework (except for the course of mathematics) for the first two years, after completion of which, specific courses of the individual programme are taught. The other three programmes viz. Statistics, Economics and Computer Science form the other group where courses are shared. This design of academic programme was adopted to make the science students learn basic fundamentals of all the science streams. Hence the students of biotechnology programme will learn basic courses related to biology and also other discipline e.g. chemistry, physics, mathematics, environmental science. Integrated M.Sc. programmes of the university were conceptualized to generate skilled manpower capable of taking inter-disciplinary approach to understand and solve real problems.

Doctor of Philosophy

Based on the expertise of faculty members, department is offering Ph. D. in upfront areas of research, which include functional genomics of abiotic stress and root development; cell signalling and human disease; Microbial physiology, genetics and ecology; Biophysics, protein chemistry and structure biology of amyloid; Vaccine development, antibody engineering and structure biology; Biophysics and infection biology; Nanotechnology for targeted drug, gene and siRNA delivery etc. A stipend of Rs. 8000/- is provided to all the candidates who make to the program.

Syllabus- Pre-Ph.D. Biotechnology

Phd Students

Sl. No	Name	Year of Joining	Supervisor	Research Area
1.	Ms. Usha Kantiwal	2016	Dr. Janmejay Pandey	Determination of anti-biofilm therapeutics.
2.	Ms. Anjana Sharma	2019	Dr. Suman Tapryal	Screening, synthesis and inhibitory analysis of potential anti-dengue molecules.
3.	Ms. Chandrika Mittal	2019	Dr. Jaykant Yadav	Studies on amyloid-like protein(s) from human cataract lens.
4.	Ms. Chhavi Choudhary	2019	Dr. Jayendra N Shukla	Sex determination and differentiation in Tribolium castaneum.
5.	Mr. Keshav Meghwanshi	2019	Dr. Jayendra N Shukla	Sex determination and differentiation in Mosquitoes.
6.	Ms. Pragya Gehlot	2019	Dr. Pankaj Goyal	Characterisation of Plasminogen Activator Inhibitor 1, a protease inhibitor.
7.	Ms. Shweta Malik	2019	Dr. Jaykant Yadav	Identification and characterisation food-derived amyloids.
8.	Mr. Sujeet Singh	2019	Dr. Tarun Bhatt	Green synthesis of metallic nanoparticles and their potential role in malarial research.
9.	Mr. Abhishek S Yadav	2020	Dr. Jaykant Yadav	Detection of amyloid(s) in gluten-rich processed food.
10.	Ms. Arpana Yadav	2020	Dr. Pankaj Goyal	Characterisation of STK-35 L1 in human diseases.
11.	Ms. Himani Tripathy	2020	Dr. Tarun Bhatt	Identification of non-invasive diagnostic markers for malaria.
12.	Ms. Preshita Bhalerao	2020	Dr. Tarun Bhatt	Design and development of novel diagnostic markers for malaria.
13.	Ms. Saloni Bage	2020	Dr. Pankaj Goyal	Identifications of novel mutations specific to breast cancer.
14.	Ms. Lacy Loveleen	2021	Dr. Surendra Nimesh	Exploring the anti-microbial activity of silver nanoparticles.
15.	Ms. Ragini Dolhey	2021	Dr. Janmejay Pandey	Plant microbe interaction
16.	Ms. Sundaram Shilpi	2021	Dr. Jayendra N Shukla	Insect- Plant interaction

Regular

Prof. Gajanan B Zore

Professor

M. Sc. Ph. D. (Biotechnology)

prof.zore_bt@curaj.ac.in

8605632007

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Professor

M.Sc. Biotechnology; M.Tech. Biotechnology; Ph.D. (Human Biology; University of Munich (LMU), Munich, Germany),CSIR- UGC NET JRF; ASRB-NET; GATE

pankaj_bio@curaj.ac.in

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Dr. Tarun Kumar Bhatt

Associate Professor

M.Sc. Biotechnology: MKU, Madurai (NET-JRF), Ph.D. Computational and Malaria Biology: ICGEB, New Delhi, PostDoc. Structural Biology: The Scripps Research Institute, San Diego, USA

tarun@curaj.ac.in

91

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Other

Dr. Surendra Nimesh

Assistant Professor

M.Sc. Biomedical Science, Dr. B.R. Ambedkar Center for Biomedical Research(ACBR), University of Delhi, Delhi; NET-JRF(Dec. 2000); PhD.(Nanotechnology), ACBR, DU(2007); Postdoctoral Research: Ecole Polytechnique of Montreal, Montreal, Canada(2007-2009)

surendranimesh@curaj.ac.in

91

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Department of Biotechnology has following laboratory facilities:-

Animal Cell culture facility, Plant Tissue culture facility and Green house, Insect culture and insect cell culture facility

Fermenter facility, Mammalian cell transfection system, Incubator shaker for bacterial growth and assays

Nanodrop, spectrophotometer and Gel documentation system

Refrigerated centrifuge, PCR machine, Sonicator

Department of Biotechnology has laboratories specific to the research interest of faculties, which includes-

1. Laboratory of Cell Biology

2. Laboratory of Immunology

3. Laboratory of Bacterial Genetics

4. Laboratory of Ameloid Biology

5. Laboratory of Vaccine Biology

6. Laboratory of Nanotechnology

7. Laboratory of Molecular Genetics

8. Laboratory of Plant Molecular Biology

Besides subject specific laboratories and facilities, Department of Biotechnology has a lab for Undergraduate students, a lab for Post graduate students and Central Instrumentation Facility (CIF) to be used by M.Sc. and PhD students. Department possesses a well equipped Bioinformatics lab also.

Research Grant received from different agencies during the last five years:

Total Amount (Rs) and Number of Research Projects: 646.17 lakhs

Name of the Investigator	Title of the project and duration	Amount sanctioned (Rs. In Lacs)	Funding Agency
Prof. A. K. Gupta	Functional Characterization of a heat shock Protein (HSP90), Amino Acid Transporter (AAT), and Nucleosome Assembly Protein (NAP) genes for their role in root development in tomato (2014- 2017)	51.46	DBT, Govt. of India
Dr. Pankaj Goyal (mentor of Dr. Deepika)	Development and q-PCR based statistical optimization of bioprocess for production of PGPR associated with cluster bean (Cyamopsis tetragonoloba) cultivars (2014- 17)	29.5	DST WoS -A Ministry of Sci. & Tech. Govt. of India
Dr. Pankaj Goyal	How lysophospholipids (Lysophosphatic acid and sphingosine -1- phosphate) metabolic pathway regulate placental development during pregnancy maintenance (Approved for funding)	50.0	DBT, Govt. of India
Dr. Pankaj Goyal (Scientific Mentor for Dr. Indu Shekhwat)	Studies on the role of sphingosine kinases in pregnancy maintenance and disorder (2016- 18)	19.20	National Postdoctoral Fellowship Project. DST, Govt. of India
Dr. Pankaj Goyal (Scientific Mentor for Dr. Vijay Kumar)	Investigating the role of Rho-GTPases pathways and adhesion proteins in decidualization and embryo implantation. (2017- 19)	19.20	National Postdoctoral Fellowship Project. DST, Govt. of India
Dr. Janmejay Pandey	Comparative analysis of soil microbial diversity across textile waste- water effluent stream(s) of Sanganer Region, Rajasthan (2014-2018)	22.70	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Tarun K. Bhatt	Molecular Modeling of malaria parasitesecretome: A potential drug target (2013- 16)	16.74	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Tarun K. Bhatt	Biochemical and structural studies on two secretory proteins of plasmodium falciparum (2014- 16)	6.00	UGC, Govt. of India
Dr. Tarun K. Bhatt	In silico screening of apicoplast proteome: In search of potential anti- malarials (2014- 17)	24.76	BRNS, DAE, Govt. of India
Dr. Tarun K. Bhatt	Molecular and structural characterization of Mitochondrial DNA Primase in Leishmania donovani (2016-19)	44.5	DBT Twinning, Govt. of India
Dr. Tarun K. Bhatt	Development and screening of potential anti-malarials based on priviledged scaffolds (2017- 20)	6.0	DST, Govt. of Rajasthan
Dr. Tarun K. Bhatt	Design, synthesis and In silico/ in vitro studies of cladospori derivatives as potential anti-malarial agents (Multi-institutional with ICGEB & HCU) (2018-21)	15.0	DST, Govt. of India
Dr. Suman Tapryal	Anti- chickengunya Ig- Viral envelope protein E2 chimeric vaccine (2014- 17)	6.00	UGC, Govt. of India
Dr. Suman Tapryal	Development of multimeric glycoprotein D- Ig µ chain fusion, subunit vaccine against Herpes Simplex virus- 2 (2016- 19)	29.0	DST, Govt. of India
Dr. Suman Tapryal	Development of glycoprotein E1/E2 immunoglobulin (Ig) chimeric subunit vaccine candidates against chickengunya virus in E.coli (2017- 20)	34.0	DST, Govt. of India
Dr. Jay Kant Yadav	Assessment of amyloidogenic propensities of HIV infection enhancing peptide PAP (2013- 16)	19.00	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Jay Kant Yadav	Targeting crystallin-amyloids for the development of non-invasive therapeutic strategy for treatment of age-related cataract	30.00	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Surendra Nimesh	Novel receptor targeted nanotechnology based gene silencing approach to suppress metabolic function of PCSK9 gene for treatment of hypercholesterolemia (2013- 2016)	18.90	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Surendra Nimesh	Nanotechnology based delivery vector for targeted drug/ gene delivery for treatment of cancer and hypercholesterolemia (2014- 15)	6.00	UGC, Govt. of India
Dr. Surendra Nimesh	Nanoparticle aided delivery of siRNA for the treatment of breast cancer (2015- 18)	25.0	DBT, Govt. of India
Dr. Surendra Nimesh	Polymeric Nanoparticle mediated locked nucleic acid delivery for the treatment of breast cancer (2015- 18)	15.33	UGC, Govt. of India
Dr. Surendra Nimesh	Design of a microbial process for the removal of organophosphorus pesticides in water supplies from rural and urban water bodies”	14.88	DST, Govt. of India and National Council for Science and Technology (CONACYT), United Mexican States
Dr. Jayendra N. Shukla	Ramalingamswami Re-entry fellowship	22.5 (Research Grant)	DBT, Govt. of India
Dr. Jayendra N. Shukla	Identification of sex-determining signal(s) and sexual differentiation factors in the red flour beetle, Tribolium castaneum.	50.0	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Jayendra N. Shukla	Identification and characterisation of genes involved in the sex determination pathway of Callosobruchus maculatus.	10.0	UGC, Govt. of India
Dr. S. T. Vaiphei	Validation studies of radiation induced genes as potential molecular biomarkers of stress response	10.0	UGC, Govt. of India
Dr. S. T. Vaiphei	Identification of candidate radiation response gene(s) (RRG) in human peripheral blood lymphocytes (PBL) for use as a molecular biomarkers	28.0	DST- SERB Ministry of Sci. & Tech. Govt. of India
Dr. Vivek Verma	Ramalingamswami Re-entry fellowship	22.5 (Research Grant)	DBT, Govt. of India

Achievement Title	Attached File
1) Department of Biotechnology recieved DBT-sponsored M.Sc Biotechnology program in year 2020. 2) Department of Biotechnology recieved DST-FIST grant (2 Crores) in year 2022.

Achievement Title

Attached File

1) Department of Biotechnology recieved DBT-sponsored M.Sc Biotechnology program in year 2020.

2) Department of Biotechnology recieved DST-FIST grant (2 Crores) in year 2022.