Personal Information

Dr. Deeksha Tripathi

Assistant Professor
Department of Microbiology

MSc. (Microbiology; University of Delhi), PhD (Biotechnology; Jawaharlal Nehru University), PostDoctoral -IIT Delhi, Visiting Scientist- Neuroscience, Physiology, Pharmacology Department, University College London, UK, AMI Young Scientist Award, CSIR-JRF

deeksha.tripathi@curaj.ac.in
  • Infection Biology
  • Antimicrobial Resistance
  • Host-Pathogen interactions
  • Mycobacterium tuberculosis: dormancy and persistence
  • Drug Designing
  • Vaccine Development

 

EMPLOYMENT DETAILS

 Assistant Professor

 

SIRE Fellow

 

Department of Microbiology, Central University of Rajasthan, India. (December 2016- Present)

UCL Department of Neuroscience Physiology & Pharmacology, University College London, Gower Street, London, WC1E 6BT (2022-23), SERB-SIRE grant

Postdoctoral Scholar

School of Biological Sciences, Indian Institute of Technology, Delhi. (2015-2016)

Assistant Professor(Adhoc)

Department of Microbiology, Gargi College, University of Delhi, New Delhi, India. (2014-2015)

EDUCATION

   PH.D. (Biotechnology)

School of Biotechnology, Jawaharlal Nehru University, New Delhi

 (2009-2014)

M.SC. (Microbiology)

University of Delhi, South Campus

(2007-2009), 71.5% (Rank 3rd in university)

B.SC. (Microbiology)

 

                     

                                                            

Institute of Home Economics, University of Delhi

(2004-2007), 74.8% (Rank 5th in university)

 

 

 

 

  • Awards

  • Young Faculty Award 2025- Oral Presentation, TIBS-2025 (International Conference), JNU, New Delhi

  • AMI – YOUNG SCIENTIST AWARD 2015 (MEDICAL & VETENARY MICROBIOLOGY)

  • National Postdoctoral Fellowship DST- SERB 2016

  • DBT RESEARCH ASSOCIATESHIP AWARD 2015

  • ICMR International Travel Grant for ASM general meeting 2014 for poster presentation.

  • ASM 2014 Student Travel Grant for poster presentation.

  • Young Scientist Award (Women category) for oral presentation in National Symposium on Microbes in Health and Agriculture. (Under UGC resource networking) (MHA-2012), School of Life Sciences, JNU, New Delhi, India, 12-13 March 2012.

  • Awarded Best Title for the Abstract in ASM Virtual Workshop on Scientific Writing and Publishing (ASM 2012), KIIT University, Bhubaneswar, Odisha, India, November, 22 2012.

  • CSIR-JRF and SRF Senior research fellowship (2009-2014)

  • Monsanto Scholarship during MSc Microbiology (2007-2009).

My research primarily investigates host-pathogen interactions, with a specific focus on Mycobacterium tuberculosis mechanisms of dormancy and persistence to inform drug designing and vaccine development. I am actively exploring the immunomodulatory potential of Mycobacterium indicus pranii (MIP) as a surrogate model for tuberculosis research and its protective effects in neurodegenerative conditions like Alzheimer’s Disease. Additionally, my work delves into the functional characterization of stress adaptation mechanisms, including Toxin-Antitoxin modules and Peptidyl-prolyl cis/trans isomerases (PPIases), to understand their roles in bacterial virulence and stress response. I am also engaged in identifying novel therapeutic interventions against anthrax and studying biofilm formation in pathogenic microorganisms. My laboratory is currently involved in establishing a BSL-3 facility to further infectious disease therapeutics and diagnostics.

S. No. Authors Title of Article Journal/Conference Details Journal/Conference Publication Year
1 Bahl, K. Negi, A. Anupam, S. Choudhary, S. Kant, S. Pandey, D. Tripathi. Resilience to stress and antibiotics, coupled with immunomodulatory behavior, uncovers Mycobacterium indicus pranii as a suitable surrogate model for tuberculosis research. Biochemical and Biophysical Research Communications, Volume 777, 2025,152296, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2025.152296 Journal 2025
  1.  Bahl A, Rajagopalan M, Rakshit R, Kant S, Pandey S, Tripathi D. (2025) Toxin–Antitoxin Modules: Genetic Elements with Many Faces and Functions. Bacteria. 2025; 4(4):61. https://doi.org/10.3390/bacteria4040061
  2.  Rakshit R, Bahl A, Gautam G, Pandey S, Tripathi D. (2025) Structure-based identification of small molecule inhibitors targeting trigger factor and peptidyl prolyl cis/trans isomerase B (PpiB) of Bacillus anthracis Sterne: Towards new therapeutic interventions against anthrax. Journal of molecular graphics & modelling, vol. 142 109185. 3 Oct. 2025, 10.1016/j.jmgm.2025.109185.    IF- 3.
  3.  Bahl, K. Negi, A. Anupam, S. Choudhary, S. Kant, S. Pandey, D. Tripathi. (2025) Resilience to stress and antibiotics, coupled with immunomodulatory behavior, uncovers Mycobacterium indicus pranii as a suitable surrogate model for tuberculosis research. Biochemical and Biophysical Research Communications, Volume 777, 2025,152296, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2025.152296. IF-2.2

  4. Raunak, R., Rakshit, R., Bahl, A., Sinha, S., Pandey, S., Kant, S., & Tripathi, D. (2025). Functional Characterization of MIP_07528 of Mycobacterium indicus pranii for Tyrosine Phosphatase Activity Displays Sensitivity to Oxidative Inactivation and Plays a Role in Immunomodulation. Biology, 14(5), 565. 10.3390/biology14050565 ,(ISSN:0739-1102), IF-3.5.

  5. Rakshit, R., Bahl, A., Arunima, A., Pandey, S., & Tripathi, D. (2025). Beyond protein folding: The pleiotropic functions of PPIases in cellular processes and microbial virulence. Biochimica et Biophysica Acta (BBA) - General Subjects, 1869(2), 130754. (ISSN: 0304-4165), IF-2.2.

  6. Bahl A, Pandey S, Rakshit R, Kant S, Tripathi D. (2024). Infection-induced trained immunity: a twist in paradigm of innate host defense and generation of immunological memory. Infection and Immunity 0:e00472-24. (ISSN: 1098-5522), IF-2.8.

  7. Tripathi Deeksha , Garg Rajni ,(2024), Editorial: Host-pathogen crosstalk: implications in host cellular processes by intracellular pathogens, Frontiers in Microbiology, VOLUME=15, DOI=10.3389/fmicb.2024.1508345. ISSN=1664-302X, IF-4.5.

  8. A Bahl, R Rakshit, S Pandey, D Tripathi, (2024) Genome wide screening to discover novel toxin–antitoxin modules in Mycobacterium indicus pranii; perspective on gene acquisition during mycobacterial evolution, Biotechnology and Applied Biochemistry, 10.1002/bab.2651, IF -3.5

  9. Khawary M, Pandey S, Sharma O, Raunak, Sharma M, Malik R, Tripathi D, (2023), Identification of novel inhibitors for Trigger Factor (TF) of M. tb: An in silico investigation, Journal of Biomolecular Structure and Dynamics, 1-8, DOI: 10.1080/07391102.2023.2218937, IF = 5.235, (ISSN:0739-1102) IF-2.7

  10. Khawary M, Rakshit R, Bahl A, Juneja P, Kant S, Pandey S, Tripathi D, (2023) M.tb-Rv2462c of Mycobacterium tuberculosis Shows Chaperone-Like Activity and Plays a Role in Stress Adaptation and Immunomodulation, Biology; 12: 69. 10.3390/biology12010069; (ISSN: 2079-7737), IF-3.5.

  11. Pandey S, Kant S, Khawary M, Tripathi D (2022); Macrophages in Microbial Pathogenesis: Commonalities of Defense Evasion Mechanisms, Infection and Immunity, DOI:10.1128/IAI.00291-21 (ISSN 0019-9567) IF-2.8

  12. Tripathi D, Kant S, Pandey S, Ehtesham NZ (2020), Resistin in Metabolism, Inflammation and Diseases, The FEBS Journal, DOI: 10.1111/febs.15322, (ISSN: 1742-464X) IF- 4.2

  13. Pandey S, Yadav B, Pandey A, Tripathi T, Khawary M, Kant S, Tripathi D (2020); Lessons from SARS-CoV-2 Pandemic: Evolution, Disease Dynamics and Future, Biology; 9:141;  DOI:10.3390/biology9060141, (ISSN: 2079-7737) , IF=3.79

  14. Kumar A#, Alam A#, Tripathi D, Rani M, Khatoon H, Pandey S, Ehtesham NZ, Hasnain SE (2018); Protein adaptations in extremophiles: An insight into extremophilic connection of mycobacterial proteome, Seminars in Cell and Developmental Biology, 84:147–157 DOI: 10.1016/j.semcdb.2018.01.003, (UGC Journal No 35747) (ISSN 1084-9521) # Authors contributed equally, IF=6.6

  15. Hasnain SE, Ehtesham N Z, Tripathi D, Grover S, Kumar A, Alam A, Pandey S (2020) A medicament for the treatment of diseases by biofilm forming microorganisms, PATENT Publication (USA, Application Number 16607061)

  16. Kumar A#, Alam A#, Grover S#, Pandey S#, Tripathi D, Kumari M, Rani M, Singh A, Akhter Y, Ehtesham NZ, Hasnain SE (2019), Peptidyl-prolyl isomerase-B is involved in Mycobacterium tuberculosis biofilm formation and a generic target for drug repurposing-based intervention. npj Biofilms and Microbiomes, 84:147–157, #equal first author; DOI:10.1038/s41522-018-0075-0; (ISSN No 2055-5008), IF = 6.33

  17. Pandey S#, Tripathi D#, Khubaib M#, Kumar A, Shaikh J, Ehtesham NZ, Hasnain SE, (2017) Mycobacterium tuberculosis peptidyl-prolyl isomerases show immunogenicity, alter cytokine profile and aid in intraphagosomal survival, Frontiers in Infection and Cellular Microbiology 7:38, DOI: 10.3389/fcimb.2017.00038, (UGC J number. 17720) (ISSN 2235-2988) # Authors contributed equally, IF = 4.3

  18. Pandey S, Sharma A, Tripathi D, Kumar A, Khubaib M, Bhuwan M, Chaudhuri TK, Hasnain SE, Ehtesham NZ; (2016). Mycobacterial peptidyl-prolyl isomerases show chaperone like activity; in vitro and in vivo; Plos One 11(3):e0150288, DOI: 10.1371/journal.pone.0150288, (UGC Journal no 37933) (ISSN 1932-6203), IF = 2.8

  19. Tripathi D, Kant S, Garg R, Bhatnagar R (2015) Low expression level of glnA1 accounts for absence of cell wall associated poly-L-glutamate/glutamine in Mycobacterium smegmatis. Biochem Biophys Res Communications, 458:240-245. DOI:10.1016/ j. bbrc.2015.01.079. (ISSN: 0006-291X), IF=2.5

  20. Garg R, Tripathi D, Kant S, Chandra H, Bhatnagar R, Banerjee N (2014). A conserved hypothetical protein Rv0574c is required for cell wall integrity and virulence of Mycobacterium tuberculosis. Infection and Immunity, 83:120-129. DOI:10.1128/ IAI.02274-14. (ISSN 0019-9567), IF=2.7

  21. Tripathi D, Chandra H, Bhatnagar R (2013) Poly-L-glutamate/glutamine synthesis in the cell wall of Mycobacterium bovis is regulated in response to nitrogen availability.                                  BMC Microbiology, 13:226. DOI:10.1186/1471-2180-13-226, (ISSN: 1471-2180), IF=3.1

  22. Rahi A, Rehan M, Garg R, Tripathi D, Lynn AM, Bhatnagar R (2011) Enzymatic characterization of catalase from Bacillus anthracis and prediction of critical residues using information theoretic measure of relative entropy. Biochem Biophys Res Commun 411:88–95. DOI:10.1016/j.bbrc.2011.06.099. (ISSN: 0006-291X), IF=2.2

SERB International Research Experience (SIRE) (2022-2023) – 16 Lakhs: “Alzheimer's Disease: Methods for investigating protective effects in mouse brain of Mycobacterium indicus pranii, A saprophytic mycobacterium with immunomodulatory and Antitubercular properties”(File No: SIR/2022/000220).PI

DST SERB Intensification of Research in High Priority Area (IRHPA) Grant (2022-2027) 9.6 crores: Creation of a BSL-3 facility at CURAJ under Rajasthan Biocluster for infectious diseases, therapeutics and diagnostics (File no-IPA/2021/000196), Co-PI

DBT Biocare grant 2019-2022 -55 Lakhs, “Identifying the role of Mycobacterium indicus pranii (MIP) in activating host innate immune response for development of new intervention strategy to combat tuberculosis. PI

UGC Startup grant (2017-2019)-10 Lakhs, “Functional Characterization of FKBP type peptidyl-prolyl cis/ trans isomerase of M. tuberculosis for its role in stress response of the pathogen”. PI

Attended

  1. Invited Lecture on “Novel Pyrazolo[4,3-c]pyridine and 1,4-diazepane Derivatives as Inhibitors of Protein Tyrosine Phosphatase B: A Promising Therapeutic Strategy Against Mycobacterium tuberculosis” on October 29, 2025 in ASM-IISc Symposium on the One Health Approach to AMR at IISc Bengaluru.
  2. Invited Lecture on “Exploring novel drug targets; Advances in Anti-tubercular drug development through structure guided approach” on October 8, 2025 at DBT-supported Conference on "Emerging Strategies and Innovations for Combating Diseases in Animals and Plants (ESCAP)" at Amity University Rajasthan.
  3. Invited Lecture in MICROArMor 2.0 during Antimicrobial resistance (AMR)- Awareness week “Tackling drug resistant in tuberculosis: new insights into an old bug”, on 18th and 19th November at Central University of Tamil Nadu. 
  4. Invited Lecture on “Bioinformatics: Scope and applications” on 30 September 2024, Diamond Jubilee series organized by CMP College, University of Allahabad
  5. Invited Lecture on “Transcriptomics; Analysis of Gene expression” on 1 October 2024, Diamond Jubilee series organized by CMP College, University of Allahabad
  6. Invited Lecture on “Mycobacterium tuberculosis, New insights into an old bug.” on 18 July 2023, PDP organized by Amity University, Manesar
  7. Invited Lecture on “Fungal disease the emerging threat to human health” on 29.05.21 at Govt. Nehru PG Collage, Rajnandgaon (C.G.)
  8. Invited Lecture on Transcriptomics: Analysis of gene at the Transcriptional Level, at Modern Biology with focus on infectious disease, at JH Institute of Molecular Medicine, Jamia Hamdard, New Delhi, India at Nov, Dec,14, 2019.
  9. Invited Lecture on “Biosensor: Current Trends” in the National workshop on Sensor Networks, Internet of Things and internet of Everything, on September 12, 2019 at Pachhunga University Collage, Mizoram, India.
  10. Invited Talk on “Mycobacterium tuberculosis: New Insight into an old bug” on Aug 24, 2018 organized by Department of Botany, CMP Collage, University of Allahabad.
  11.  Invited Lecture on “Application of Microbiology in Agriculture and Industries” on August 23, 2018 at Department of Botany, CMP College, Allahabad.
  12. Participated in, Annual Herpesviruses: Pathogenesis and Cancer Symposium organized by Tumor virology program, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA on, June 23, 2017.
  13. Participated in The Noreen O'Neill Melanoma Research Symposium at The Wistar Institute, the cancer institute distinguished by National Cancer Institute, Philadelphia, PA, USA on June 5, 2017.
  14. Tripathi D, Garg R, Kant S, Bhatnagar R. Comparative study of glnA1 promoter of M. bovis and M. smegmatis; its implications on poly-α-L-glutamine (PLG) synthesis in the cell wall of mycobacteria. 114th General Meeting, American Society for Microbiology (ASM 2014), Boston, Massachusetts, USA, 17-20 May 2014. 
  15. Tripathi D, Chandra H, Garg R, Kant S, Bhatnagar R. Comparative study of glnA1 promoter of Mycobacterium bovis and Mycobacterium smegmatis; its implications in poly-α-L-glutamine (PLG) synthesis in the cell wall of mycobacteria. National Symposium on Microbes in Health and Agriculture. (Under UGC resource networking) (MHA-2012), School of Life Sciences, JNU, New Delhi, India, 12-13 March 2012 (Oral Presentation)- 1st prize for Young Scientist Award.
Title Attachment File Other Link
Resume PDF icon CV Deeksha- November 2025.pdf